• Supplemental Vitamin C Abolishes Brain Plaque

    Posted April 12, 2021: by Bill Sardi

    Modern medicine has finally realized its many experiments with laboratory mice have been flawed by the failure to recognize humans do not secrete vitamin C as rodents do. Therefore, many scientific studies performed in mice have little application to humans.

    Unlike most other animals, patients with Alzheimer’s disease have a progressive buildup of beta amyloid plaque in their brains and loss of memory. Researchers now think they have found out why.

    Unexpected discovery

    Guinea pigs, fruit bats, and primate monkeys as well as humans do not secrete vitamin C as other mammals do. A universal gene mutation is shared by these species.

    Laboratory mice naturally secrete vitamin C continually throughout the day and night. When lab animals are genetically altered so they do not secrete vitamin C internally, they accumulate beta amyloid brain plaque like humans do.

    Conversely animals that are supplemented with vitamin C to the same vitamin blood level as animals that naturally secrete vitamin C, no brain plaque is found.

    Furthermore, in this experiment, the vitamin C- supplemented animals also exhibited stronger blood capillaries and their cell energy compartments (mitochondria) were more functional.

    Some mice in the laboratory were given low amounts of vitamin C and did not exhibit eradication of their brain plaque.

    Brain Cortex And Hippocampus

    These deleterious changes occurred in the frontal cortex and hippocampus of the brain.

    The cerebral cortex, the largest part of the brain, is the ultimate control and information-processing center. The Hippocampus, in the temporal lobe, is the major learning and memory center.


    Brain cells have hundreds of energy compartments in cells called mitochondria. In brain disease the mitochondria are misshapen and function poorly. The vitamin C-supplemented animals averted these age-related changes.

    Not Enough Vitamin C

    Normal dietary intake of vitamin C did not produce these same beneficial effects in these lab animals.

    Americans consume ~110 milligrams of vitamin C daily, not enough to achieve the same high blood concentrations as animals do that endogenously secrete vitamin C.

    Blood Brain Barrier

    The brain has a protective barrier called the blood-brain barrier (BBB) to keep toxins and viruses out of the nerve control center of the human body.

    The blood brain barrier is comprised of small veins and arteries called venules and arterioles. Oxygen is exchanged for CO2 in the BBB or capillaries. Low vitamin C blood levels result in weak capillaries that results in inflammation and toxicity.

    Observable Evidence

    Graphic shows beta amyloid plaque in brain cells of genetically-altered animals given low (left) and high (right) doses of vitamin C

    Researchers say: “vitamin C deficiency is directly related to amyloid plaque deposition, suggesting that sufficient dietary intake of vitamin C has a crucial role in protecting against beta amyloid plaque-induced oxidative stress.”

    The report, published in CELL DEATH & DISEASE, can be viewed online.

    Correction of genetic flaw

    Recently a correction of the mutation in humans that halts internal synthesis of vitamin C was discovered.

    A human clinical experiment show that an olive-derived molecule restores endogenous vitamin C synthesis and doubles vitamin C blood levels.

    The results of this experiment can be viewed online. Both urine and blood serum studies were conducted.

    This discovery remarkably indicates a simple remedy for Alzheimer’s disease has been available since the discovery of vitamin C by Albert Szent-Györgyi in the 1930’s. In that same decade vitamin C was synthetically made, making it possible to add vitamin C to foods and consume as a dietary supplement.

    Modern drugs commonly prescribed for Alzheimer’s have been shown to be no better than an inactive placebo.

    Efforts to cure or prevent Alzheimer’s with a blockbuster drug led modern medicine in the wrong direction.

    Tragically, there are many more elderly Americans suffering from Alzheimer’s disease today than there were in the 1930’s –- 6.2 million in the U.S. alone.

    To duplicate the animal experiment humans would have to consume supplemental vitamin C throughout the day and night. Obviously, animals that internally secrete vitamin C have a distinct advantage. They even secrete vitamin C during sleep which is the body’s healing period.

    The recent discovery how to restore vitamin C synthesis in humans has been overlooked. It is a momentous and long overdue breakthrough. It doubles vitamin C blood levels without consumption of vitamin C-rich foods or supplements. The manufacturer says the  product has worked without fail so far.

    Consumers can test whether the product raises urine levels with the use of urine test strips.

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