• The Incredible Shrinking (Mushy) Vitamin B-12 Deficient Brain

    Posted September 11, 2013: by Bill Sardi

    Investigators at Tufts University display striking images of the human brain when it is deficient in vitamin B12.  Brain scans show fluid-filled spaces at the center of a shrinking B-12 deficient brain – literally holes in the brain.

    A prior study showed that high-dose B vitamins (800 mcg folic acid, 20 mg vitamin B6, 500 micrograms of vitamin B12) slows the rate of shrinkage in the human brain, and more demonstrably reduces (by 7 times) shrinkage of grey matter in the brain.

    This study, published in the Journal of the American Geriatrics Society, is more striking because of the photographic images of a shrinking brain accompanied by mental tests which confirms loss of thinking ability as the brain shrinks in size.

    Lack of absorption of dietary and supplemental vitamin B12 due to progressive inability to produce stomach acid is cited as a growing concern.  Therefore, it may be that widespread H. pylori infection, which is prevalent in more than half of the US population, could be a parallel facto as H. pylori shuts down production of stomach acid.

    Another concern is that the most often used anti-diabetic drug, metformin, depletes the body of vitamin B12.  Metformin use has been associated with declining mental function.  ©2013 Bill Sardi, Knowledge of Health, Inc.

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